
Journal of Fluorine Chemistry p. 561 - 574 (1983)
Update date:2022-07-30
Topics:
Middleton, W. J.
Bingham, E. M.
Several novel α-trifluoromethylarylacetic acids were synthesized, utilizing chloropentafluoroacetone as the source of the trifluoromethyl group.One of these new acids, the trifluoro-analog (30) of ibuprofen, showed antiinflammatory, analgesic, and ulcerogenic properties similar to ibuprofen.
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Doi:10.1002/ardp.19843170213
(1984)Doi:10.1016/j.tetasy.2007.05.014
(2007)Doi:10.1007/s11172-005-0293-5
(2005)Doi:10.1021/ja01126a068
(1952)Doi:10.1007/BF00523071
(1983)Doi:10.1016/S0040-4020(01)87440-8
(1986)