Improved preparation of β-hydroxy-α-amino acids: Direct formation of sulfates by sulfuryl chloride

Article abstract of DOI:10.1016/j.tetasy.2005.10.013

Two β-(alkyl)-β-hydroxy-α-amino acids [alkyl = Bu ^t, BnO-(CH₂)₃-] have been synthesized by a sequence based on Sharpless asymmetric dihydroxylation. The key sulfate intermediates were prepared from enantiomerically enriche