Synthesis and biological evaluation of allosteric A1-adenosine receptor modulators structurally related to (2-amino-4,5,6,7-tetrahydro-benzo[b] thiophen-3-yl)-(4-chloro-phenyl)-methanone, a potent compound useful to reduce neuropathic pain

Article abstract of DOI:10.1007/s00044-005-0129-8

New derivatives of (2-amino-4,5,6,7-tetrahydrobenzo[b]thiophen-3-yl)-(4- chlorophenyl)-methanone (compound 1), an allosteric enhancer of agonist binding to the A₁-adenosine receptor, have been synthesized and evaluated in an intact cell assay a

Full text of DOI:10.1007/s00044-005-0129-8

Med Chem Res 14:3 (2005) 125–142
௠ Birkha¨user Boston 2005

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Received:
01-14-05
Accepted:
08-19-05
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