ENANTIOSPECIFIC SYNTHESIS OF NATURAL (+)-(S,S)-(CIS-6-METHYLTETRAHYDROPYRAN-2-YL)ACETIC ACID, A CONSTITUENT OF CIVET

Article abstract of DOI:10.1246/cl.1983.1601

(+)-(S,S)-(cis-6-Methyltetrahydropyran-2-yl)acetic acid, a constituent of the glandular secretion from the civet cat was synthesized enantiospecifically from (+)-(R,R)-diethyl tartrate via stereospecific reductive ring opening of an optically active 5,7-d