ADDITION OF TRIMETHYLSILYL CYANIDE TO α-SUBSTITUTED KETONES: CATALYSTEFFICIENCY

DOI: 10.1016/S0040-4039(00)85954-7

Source and publish data:

Tetrahedron Letters p. 4559 - 4560 (1983)

Update date:2022-09-26

Topics:

Authors:

Greenlee, W. J.

Hangauer, D. G.

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Article abstract of DOI:10.1016/S0040-4039(00)85954-7

Addition of trimethylsilyl cyanide to α-substituted ketones is often slow and incomplete when catalyzed by zinc iodide.Use of potassium cyanide/18-crown-6 complex as catalyst is a superior method, providing high yields of adducts.

Full text of DOI:10.1016/S0040-4039(00)85954-7

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