Journal of Medicinal Chemistry p. 600 - 604 (1984)
Update date:2022-08-04
Topics:
Rosowsky, Andre
Forsch, Ronald A.
Freisheim, James H.
Moran, Richard G.
Wick, Michael
Methotrexate (MTX) and aminopterin (AMT) analogues containing L-homocysteic acid or L-cysteic acid in place of L-glutamic acid were synthesized and tested as inhibitors of dihydrofolate reductase from L1210 cells and folyl polyglutamate synthetase from mo
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