Bicyclic Lactam Inhibitors of Angiotensin Converting Enzyme

DOI: 10.1021/jm00372a022

Source and publish data:

Journal of Medicinal Chemistry p. 816 - 818 (1984)

Update date:2022-08-04

Topics:

Authors:

Watthey, Jeffrey W. H.

Gavin, Terrence

Desai, Mahesh

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Article abstract of DOI:10.1021/jm00372a022

Syntheses of the potent angiotensin converting enzyme inhibitor 1-(carboxymethyl)-3-(mercaptomethyl)-2,3,4,5-tetrahydro-1H-1-benzazepin-2-one (4a) and the corresponding eight-membered ring analogue (4b) are described.The influence of ring size on the inhi

Full text of DOI:10.1021/jm00372a022

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