Bicyclic Lactam Inhibitors of Angiotensin Converting Enzyme

DOI: 10.1021/jm00372a022

Source and publish data:

Journal of Medicinal Chemistry p. 816 - 818 (1984)

Update date:2022-08-04

Topics:

Authors:

Watthey, Jeffrey W. H.

Gavin, Terrence

Desai, Mahesh

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00372a022

Syntheses of the potent angiotensin converting enzyme inhibitor 1-(carboxymethyl)-3-(mercaptomethyl)-2,3,4,5-tetrahydro-1H-1-benzazepin-2-one (4a) and the corresponding eight-membered ring analogue (4b) are described.The influence of ring size on the inhi

Full text of DOI:10.1021/jm00372a022

Products guided by the article

Product name:1H-1-Benzazepine-1-acetic acid, 2,3,4,5-tetrahydro-2-oxo-3-[(phenylthio)methyl]-, ethyl ester

Cas No:89177-65-1

R&D Labs maybe for 89177-65-1

Tianjin Dongchang Fine Chemical Industry Co., Ltd.

Contact:+86-22-29894595

Address:Economic Developing Zone, Ji County, Tianjin, China
Beijing Zhongshuo Pharmaceutical T & D Co.,Ltd

Contact:0086-10-64430626

Address:ea No 16, HEPINGLI,DONGCHENG DISTRICT,BEIJING,P.R.CHINA.
Zhejiang Tianyu Pharmaceutical Co., Ltd.

Contact:+86-576-84177669, 89189665,89189688,84168770

Address:Jiangkou Development Zone, Huangyan, Taizhou City, Zhejiang
Zhejiang Golden-Shell Pharmaceutical Co.,Ltd.

Contact:+86-576-87501888 / 87501988

Address:No.89 Zhongxing Road. Li'ao, Yuhuan, Zhejiang, China
Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd.

website:http://www.shydtec.com

Contact:86-21-57721279

Address:Science and Technology Park, Songjiang District, Shanghai, China

Relevant to this article

Parallel anti-sense two-step cascade for alcohol amination leading to ω-amino fatty acids and α,ω-diamines

Doi:10.1039/c8gc02122h
(2018)
Stereoisomers of Allenic Amines as Inactivators of Monoamine Oxidase Type B. Stereochemical Probes of the Active Site

Doi:10.1021/jm00403a012
(1988)
Synthesis, characterization, and biological evaluation of novel ferrocene-triadimefon analogues

Doi:10.1016/j.jorganchem.2005.11.029
(2006)
Generation of the Dianion of N-(Trimethylsilyl)acetamide and Reaction of the Dianion with Electrophilic Reagents

Doi:10.1021/jo00185a038
(1984)
Synthesis, characterization and study on the dissimilar reactivity of a Ni(II)-bis(iminosemiquinone) complex core to ligand-appended hemilabile –CH₂OH and –CH₂NH₂ units

Doi:10.1016/j.ica.2019.119340
(2020)
SYNTHESIS OF HETEROCYCLIC PHTHALIMIDOALKYL KETONES

Doi:10.1007/BF00505853
(1984)

Article Doi