
Helvetica Chimica Acta p. 2437 - 2442 (1983)
Update date:2022-07-30
Topics:
Schmidhammer, Helmut
Brossi, Arnold
Flippen-Anderson, Judith L.
Gilardi, Richard
Wolff-Kishner reduction of the optically active ketomorphinan 5 afforded the optically active morphinan 6 differing chromatographically and spectroscopically from the material obtained in a Grewe-cyclization of the isoquinoline 1.A single crystal X-ray analysis of a hydrobromide salt of a phenolic amine obtained from 1 and 2 with refluxing hydrobromic acid showed this compound to be the N-methylapomorphinan 4.
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