Chemoselective Acylation of Primary Amines in the Presence of Secondary Amines with Acyl Cyanides. Highly Efficient Methods for the Synthesis of Spermidine and Spermine Alkaloid

DOI: 10.1246/cl.1987.879

Source and publish data:

Chemistry Letters p. 879 - 882 (1987)

Update date:2022-07-31

Topics:

Authors:

Murahashi, Shun-Ichi

Naota, Takeshi

Nakajima, Nobuyuki

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1246/cl.1987.879

Acyl cyanides are highly useful reagents for the chemoselective acylation of primary amines in the presence of secondary amines.The reaction provides the versatile method for the shortstep synthesis of various naturally occurring polyamines.

Full text of DOI:10.1246/cl.1987.879

Products guided by the article

Product name:N¹,N⁸-bis(3,4-dimethoxybenzoyl)spermidine

Cas No:89647-71-2

R&D Labs maybe for 89647-71-2

GenicBio Limited

Contact:+86-(0)21-3770 9035

Address:Room 301, Building 2, Meijiabang Road 1508, Shanghai China
XI'AN CHUKANG BIOTECHNOLOGY CO.,LTD

Contact:29-63685658 63685359

Address:Room 3-1202,Building 1,Oriental oasis,East of Xianning Road,Xi'an,Shaanxi 710043 P.R.China
Hangzhou Zyter Biological & Chemical Technology Co., Ltd.

website:http://www.zyterpharm.com

Contact:+86-18858184290

Address:West Wenyi Road, Cangqian, Yuhang
Foreschem Co., Ltd

Contact:+86-533-3112891

Address:zibo
Sichuan Highlight Fine Chemicals Co., Ltd.

Contact:+86-28-8525 1605

Address:A5-102 Airport base,388 West Airport Huang He Zhong Lu,2 Section

Relevant to this article

Synthesis of tyrosinase inhibitory kojic acid derivative

Doi:10.1002/ardp.200500213
(2006)
Total synthesis of (+)-yatakemycin

Doi:10.1021/ja0619455
(2006)
Macrolide Biosynthesis. 3. Stereochemistry of the Chain-Elongation Steps of Erythromycin Biosynthesis

Doi:10.1021/ja00276a042
(1986)
Catalytic ortho -acetoxylation of masked benzyl alcohols via an exo -directing mode

Doi:10.1021/acs.orglett.5b01098
(2015)
ORIENTATION SELECTIVE BOND CLEAVAGE REACTIONS OF BIPHENYL-FUSED 1,2-DIPHENYLCYCLOBUTANES INITIATED BY ELECTRON TRANSFER¹

Doi:10.1016/S0040-4039(00)89195-9
(1985)
Structure-guided design of novel l -Cysteine derivatives as potent KSP inhibitors

Doi:10.1021/acsmedchemlett.5b00221
(2015)

Article Doi