Chemoselective Acylation of Primary Amines in the Presence of Secondary Amines with Acyl Cyanides. Highly Efficient Methods for the Synthesis of Spermidine and Spermine Alkaloid

DOI: 10.1246/cl.1987.879

Source and publish data:

Chemistry Letters p. 879 - 882 (1987)

Update date:2022-07-31

Topics:

Authors:

Murahashi, Shun-Ichi

Naota, Takeshi

Nakajima, Nobuyuki

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1246/cl.1987.879

Acyl cyanides are highly useful reagents for the chemoselective acylation of primary amines in the presence of secondary amines.The reaction provides the versatile method for the shortstep synthesis of various naturally occurring polyamines.

Full text of DOI:10.1246/cl.1987.879

Products guided by the article

Product name:N¹,N⁸-bis(3,4-dimethoxybenzoyl)spermidine

Cas No:89647-71-2

R&D Labs maybe for 89647-71-2

Nanjing Manhay Medical Technology Co.,Ltd

Contact:86-25-18061468449 13951924040

Address:Building5,Fuzhong Park,Xuanwu District
Hefei EnliPharma Tecnology Co.,Ltd

Contact:0086-551-66399836

Address:Qing Cheng ShuiXiang Building 805, Mengcheng North Road , ShuangFeng Economic Development Zone Anhui HeFei
Fujian Wanke Pharmaceutical Co., LTD.

Contact:+86-598-5026002

Address:Economic development zone,jiangle county
Changzhou Ansciep Chemical Co.,Ltd.

Contact:+86 519 8630 5871

Address:A-710 Boan International, 8 East Guangdian Road,Wujin,Changzhou
Huayi Isotopes Co.

Contact:+ 86 512 52491118

Address:1 Fuyu Road, Haiyu TownChangshu, Jiangsu, China

Relevant to this article

Synthesis of tyrosinase inhibitory kojic acid derivative

Doi:10.1002/ardp.200500213
(2006)
Total synthesis of (+)-yatakemycin

Doi:10.1021/ja0619455
(2006)
Macrolide Biosynthesis. 3. Stereochemistry of the Chain-Elongation Steps of Erythromycin Biosynthesis

Doi:10.1021/ja00276a042
(1986)
Catalytic ortho -acetoxylation of masked benzyl alcohols via an exo -directing mode

Doi:10.1021/acs.orglett.5b01098
(2015)
ORIENTATION SELECTIVE BOND CLEAVAGE REACTIONS OF BIPHENYL-FUSED 1,2-DIPHENYLCYCLOBUTANES INITIATED BY ELECTRON TRANSFER¹

Doi:10.1016/S0040-4039(00)89195-9
(1985)
Structure-guided design of novel l -Cysteine derivatives as potent KSP inhibitors

Doi:10.1021/acsmedchemlett.5b00221
(2015)

Article Doi