
Tetrahedron p. 6825 - 6838 (1994)
Update date:2022-09-26
Topics: Synthesis Nucleosides Sulfamoyl Experimental
Kristinsson, Haukur
Nebel, Kurt
O'Sullivan, Anthony C.
Struber, Fritz
Winkler, Tammo
Yamaguchi, Yasuchika
The sulfamoylated ribose derivative 8 was prepared on a kilogram scale, and used in conjunction with various heterocycles to prepare a series of natural and unnatural 5-O-sulfamoyl nucleosides (10 - 32).A modification of the Vorbrueggen-Hilbert-Johnson reaction conditions for nucleoside formation was used.
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