New Nitrogenous Sesquiterpenes from the Marine Sponge Axinella cannabina

Article abstract of DOI:10.1021/jo00195a012

In addition to acanthellin-1 (1), an isonitrile previously found in Acanthella acuta, five new nitrogenous sesquiterpenes (2-6) have been isolated from the Mediterranean sponge Axinella cannabina and their structures elucidated on the basis of chemical and spectral data.These metabolites form two new isocyanide-isothiocyanate-formamide series thus confirming the biogenetical relationship between these three classes of compounds.