Studies on the Synthesis of the Antitumor Agent CC-1065. Synthesis of the Cyclopropapyrroloindole Portion

DOI: 10.1039/c39840000389

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 389 - 390 (1984)

Update date:2022-08-04

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Authors:

Magnus, Philip

Gallagher, Timothy

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Article abstract of DOI:10.1039/c39840000389

Using a regioselective Mannich reaction the 3,3'-bipyrrole (4) is converted into the acid chloride (10), which is transformed into the tricyclic phenol (11); selective reduction of (11) using triethylsilane in trifluoroacetic acid gives (12), which is con

Full text of DOI:10.1039/c39840000389

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