Synthesis and Biological Activity of 5-Thiobredinin and Certain Related 5-Substituted Imidazole-4-carboxamide Ribonucleosides

DOI: 10.1021/jm00147a013

Source and publish data:

Journal of Medicinal Chemistry p. 1198 - 1203 (1985)

Update date:2022-07-29

Topics:

Authors:

Wood, Steven G.

Upadhya, Krishna G.

Dalley, Kent N.

McKernan, Patricia A.

Canonico, Peter G.

et. al. et. al.

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Article abstract of DOI:10.1021/jm00147a013

A number of 5-substituted imidazole-4-carboxamide ribonucleosides were prepared and tested for their biological activity.Treatment of 5-chloro-1-β-D-ribofuranosylimidazole-4-carboxamide (2) with methanethiol provided 5-(methylthio)-1-β-D-ribofuranosylimid

Full text of DOI:10.1021/jm00147a013

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