Mechanistic studies leading to a new procedure for rapid, microwave assisted generation of pyridine-3,5-dicarbonitrile libraries

DOI: 10.1016/j.tet.2007.03.139

Source and publish data:

Tetrahedron p. 5300 - 5311 (2007)

Update date:2022-08-04

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Authors:

Guo, Kai

Thompson, Mark J.

Reddy, Tummala R.K.

Mutter, Roger

Chen, Beining

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Article abstract of DOI:10.1016/j.tet.2007.03.139

Mechanistic investigations into the multi-component synthesis of pyridine-3,5-dicarbonitriles have established a defined reaction pathway, particularly clarifying the role of aerobic oxidation in conversion of the intermediate 1,4-dihydropyridines into th

Full text of DOI:10.1016/j.tet.2007.03.139

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