Reissert Compound Formation with Five-membered Ring Heterocycles using Trimethylsilyl Cyanide

DOI: 10.1039/c39840001245

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 1245 - 1246 (1984)

Update date:2022-07-29

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Authors:

Uff, Barrie C.

Chen, S. L. Anne A.

Ho, Yee-Ping

Popp, Frank D.

Kant, Joydeep

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Article abstract of DOI:10.1039/c39840001245

Treatment of benzothiazole with trimethylsilyl cyanide and an acid chloride in CH2Cl2 gives the N-acyl-2-cyano-2,3-dihydrobenzothiazole in good yield; benzoxazole similarly is converted into a five-membered ring Reissert compound, providing the first exam

Full text of DOI:10.1039/c39840001245

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