3-(Acylamido)-4-phenyl-6(E)-(iodomethylidene)tetrahydro-2-pyranones. synthesis of Novel Amino Acid Analogues

DOI: 10.1021/jo00213a026

Source and publish data:

Journal of Organic Chemistry p. 2331 - 2336 (1985)

Update date:2022-08-03

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Authors:

Sofia, Michael J.

Katzenellenbogen, John A.

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Article abstract of DOI:10.1021/jo00213a026

We have synthesized the 3R^*,4R^* and 3R^*,4S^* diastereomers of two 3-(acylamino)-4-phenyl 6(E)-(iodomethylidene)tetrahydro-2-pyranones (13A,B and 14A,B) by iodolactonization of substituted 5-hexynoic acid precurso

Full text of DOI:10.1021/jo00213a026

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