REACTIONS OF 5,6-DIAMINO-1,3-DIMETHYLURACIL WITH CARBONYL COMPOUNDS

Article abstract of DOI:10.1007/BF00504210

Teh first step in the acid-catalyzed reaction of 5,6-diamino-1,3-dimethyluracil with carbonyl compounds is the formation of an azomethine at the 5-amino group.Chalcone derivatives undergo a further substitution; the 6-amino group is replaced by a hydroxyl group with subsequent ring closure and the formation of 2,3-dihydro-1,5-oxazepine ring.Azomethines based on arylidenacetones form 2,3-dihydropyrimidino<5,6-b>-1,5-diazepine derivatives.