INTRAMOLECULAR MICHAEL ADDITION REACTION TO CHIRAL VINYLIC SULFOXIDES. AN ENANTIOSELECTIVE SYNTHESIS OF (R)- AND (S)-1,7-DIOXASPIROUNDECANE

Article abstract of DOI:10.1016/S0040-4039(00)98967-6

(R)- and (S)-1,7-Dioxaspiro<5.5>undecane <(R)-1 and (S)-1>, sex pheromone of an olive fly, was each stereoselectively synthesized using an intramolecular Michael addition of hydroxyl group to a chiral vinylic sulfoxide moiety as an asymmetric induction step.