
Journal of the Chemical Society. Chemical communications p. 1298 - 1299 (1986)
Update date:2022-08-11
Topics:
Laumen, Kurt
Schneider, Manfred P.
Compound (1R,4S)-(4a), a central chiral building block for cyclopentanoid natural products, was prepared in high yield and optically pure by enantioselective hydrolysis of (5a) in the presence of several lipases, and was further transformed into (R)-(1a), (1R,5S)- and (1S,5R)-(2), (7), and (8), important synthons for this class of compounds.
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