AN IMPROVED MODIFICATION OF RITTER REACTION

DOI: 10.1016/S0040-4039(00)95260-2

Source and publish data:

Tetrahedron Letters p. 581 - 582 (1989)

Update date:2022-08-29

Topics:

Authors:

Martinez, A. Garcia

Alvarez, A. Martinez

Vilar, E. Teso

Fraile, A. Garcia

Hanack, M.

Subramanian, L. R.

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Article abstract of DOI:10.1016/S0040-4039(00)95260-2

The reaction of alcohols 1 with trifluoromethane sulfonic anhydride (Tf2O) in dichloromethane in presence of a 2:1 excess of nitriles 3 affords the corresponding amides 5 in good yields.

Full text of DOI:10.1016/S0040-4039(00)95260-2

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