Tetrahedron Letters p. 2659 - 2662 (1994)
Update date:2022-08-11
Topics:
Carson, Kenneth G.
Ganem, Bruce
Radin, Norman S.
Abe, Akira
Shayman, James A.
Synthetic 1-morpholino-1-deoxyceramides were designed to inhibit glucosylceramide synthase.The most potent inhibitor 2a possesses the unnatural R,R-configuration of D-threo-sphingosine.
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