Chemo- and stereoselective reduction of α,β-epoxyketones with diisopropoxytitanium(III) tetrahydroborate

Article abstract of DOI:10.1016/0040-4020(96)00465-6

Reduction of α,β-epoxyketones with diisopropoxytitanium(III) tetrahydroborate in dichloromethane under mild conditions (-78°→20°C) provides anti- (or erythro-) α,β-epoxy alcohols in high yields with high degree of chemo- and stereoselectivity.