Chemistry of Heterocyclic Compounds p. 528 - 533 (1983)
Update date:2022-08-11
Topics:
Potapov, V.M.
Dem'yanovich, V. M.
Vendrova, O. E.
Khlebnikov, V. A.
It is shown that mixtures of two isomeric benzolactams, viz., compounds of the benzamide and anilide type, are formed in the intramolecular amidation of arylalkylhydroxamic acids under the influence of polyphosphoric acid (PPA).A general reaction scheme that includes three pathways, viz., direct amidation, Losen rearrangement of the hydroxamic acids with subsequent cyclization of the isocyanates, and Beckmann rearrangement of the oximes of the cyclic ketones formed in the thermal cleavage of the starting hydroxamic acids in PPA, is proposed on the basis of a study of racemic and optically active arylalkylhydroxamic acids.
View More
Contact:86-512-69362780,69362785
Address:No.69 Weixin Road,Weiting Town,Suzhou Industrial Park
Contact:13120882795；+86-21-34621078;+86-021-31122318
Address:Suite 2,No.2715 Longwu Road
Contact:+86-571-86491666
Address:SHI XIANG ROAD
Hangzhou Pharma & Chem Co.,Ltd.
Contact:+86-571-87040515
Address:No,139Qingchun Rd
Hangzhou Eastbiopharm Co.,Ltd.
Contact:+86-571-88931780
Address:Hangzhou,China
Doi:10.1016/j.tetlet.2004.08.026
(2004)Doi:10.1016/S0020-1693(00)83721-4
(1981)Doi:10.1021/ma501934p
(2015)Doi:10.1002/asia.201500518
(2015)Doi:10.1021/ja054029k
(2005)Doi:10.1107/S0108270199006149
(1999)
