Tetrahedron Letters p. 2875 - 2878 (1997)
Update date:2022-08-17
Topics:
Kojima, Satoshi
Hirano, Takashi
Niwa, Haruki
Ohashi, Mamoru
Inouye, Satoshi
Tsuji, Frederick I.
A model compound, 4-(4-hydroxypheny])methylideneimidazol-5 undergoes a reversible redox reaction identical to that of the Aequorea green fluorescent protein (GFP), strongly suggesting that the GFP chromophore is derived via the autoxidation of a nonfluorescent dihydro precursor in dihydro-GFP.
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