A new method for the resolution of amines and its application to 3-amino-1,5-benzodiazepines

Article abstract of DOI:10.1016/0957-4166(95)00086-5

A new method for the resolution of racemic amines and its application to 3-amino-1,5-benzodiazepines is reported. The method is based upon the reaction of the amines with a chiral auxiliary, namely the tosyl derivative of (S)-(+)-methyl mandelate, followe