A convenient preparation of (±)-α-methoxy-α-trifluoromethylphenylacetic acid (Mosher's acid)

Article abstract of DOI:10.1080/00397919308018609

Mosher's acid can be prepared from PhC(O)CF₃ via a vinylation, methylation, ozonolysis/oxidation sequence in >80% overall yield.

Full text of DOI:10.1080/00397919308018609

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Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic Organic
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A Convenient Preparation
of (±)-α-Methoxy-α-
trifluoromethylphenylacetic Acid
(Mosher's Acid)
J. Michael Chong a & Rob Loewith a
a Department of Chemistry , University of Waterloo ,
Waterloo, Ontario, Canada , N2L 3G1
Published online: 23 Sep 2006.
To cite this article: J. Michael Chong & Rob Loewith (1993) A Convenient Preparation of
(±)-α-Methoxy-α-trifluoromethylphenylacetic Acid (Mosher's Acid), Synthetic Communications:
An International Journal for Rapid Communication of Synthetic Organic Chemistry, 23:15,
2145-2150, DOI: 10.1080/00397919308018609
To link to this article: http://dx.doi.org/10.1080/00397919308018609
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