An easy one-pot synthesis of group 14 C-metallated 2 (or 3)-furan- and thiophenecarbaldehydes

Article abstract of DOI:10.1055/s-1992-26276

The group 14 C-metallated 2(or 3)-furan- and thiophenecarbaldehydes 4-19 have been regioselectively prepared by a one-pot procedure from the corresponding furan- and thiophenecarbaldehydes using lithium N-methylpiperazide/butyllithium or sec-butyllithium/chlorotrialkylsilanes (germanes, tin)/water as sequence of reagents.