A simple and practical synthesis of (+)-2-bromobicyclo[2.2.1]hept-5-ene-2-carboxaldehyde via chiral Lewis acid catalyzed [4+2] cycloaddition

Article abstract of DOI:10.1080/00397919608003625

A chiral titanium complex derived from BINOL and Ti(O-i-Pr)4 catalyzes the Diels-Alder reaction of 2-bromoacrolein and cyclopentadiene with 97:3 enantioselectivity. Lower enantioselectivity was observed using other dienes or with methacrolein as dienophil

Full text of DOI:10.1080/00397919608003625

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A Simple and Practical
Synthesis of (+)-2-
Bromobicyclo[2.2.1]hept-5-
ene-2-carboxaldehyde via
Chiral Lewis Acid Catalyzed
[4+2] Cycloaddition
Gary E. Keck a & Dhileepkumar Krishnamurthy a
a Department of Chemistry , University of
Utah , Salt Lake City, UT, 84115
Published online: 21 Aug 2006.
To cite this article: Gary E. Keck & Dhileepkumar Krishnamurthy (1996) A
Simple and Practical Synthesis of (+)-2-Bromobicyclo[2.2.1]hept-5-ene-2-
carboxaldehyde via Chiral Lewis Acid Catalyzed [4+2] Cycloaddition, Synthetic
Communications: An International Journal for Rapid Communication of Synthetic
Organic Chemistry, 26:2, 367-373, DOI: 10.1080/00397919608003625
To link to this article: http://dx.doi.org/10.1080/00397919608003625
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