
Bulletin of the Chemical Society of Japan p. 608 - 610 (1989)
Update date:2022-08-16
Topics:
Naoshima, Yoshinobu
Hasegawa, Hidenobu
Nishiyama, Tadashi
Nakamura, Akihiro
Highly optically pure (R)- and (S)-phoracantholide I were synthesized in relatively short steps starting from diethyl 3-oxoglutarate by means of a microbial asymmetric reduction of the intermediate keto acid with immobilized baker's yeast entrapped in gels of κ-carrageenan.
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(1995)