The chemistry of the taxane diterpene: Stereoselective synthesis of 10-deacetoxy-11,12-expoxypaclitaxel

DOI: 10.1016/0040-4039(95)01928-B

Source and publish data:

Tetrahedron Letters p. 8909 - 8912 (1995)

Update date:2022-08-11

Topics:

Authors:

Harriman

Jalluri Jalluri

Grunewald

Vander Velde

Georg Georg

Himes Himes

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Article abstract of DOI:10.1016/0040-4039(95)01928-B

Epoxidation of the olefin in 10-deacetoxybaccatin III (6) and 10-deacetoxypaclitaxel (9) was accomplished with meta-chloroperbenzoic acid leading to a novel pentacyclic ring system. Hydroxyl directed delivery of the epoxidizing agent did not appear to pla

Full text of DOI:10.1016/0040-4039(95)01928-B

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