Novel N→C acyl migration reaction of acyclic imides: A facile method for α-aminoketones and β-aminoalcohols

DOI: 10.1016/S0040-4039(98)01093-4

Source and publish data:

Tetrahedron Letters p. 5537 - 5540 (1998)

Update date:2022-08-17

Topics:

Authors:

Hara, Osamu

Ito, Masao

Hamada, Yasumasa

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Article abstract of DOI:10.1016/S0040-4039(98)01093-4

The acyclic imides derived from primary benzylic amines and amino acid esters easily undergo the novel N→C acyl migration reaction via a base- generated carbanion, yielding the corresponding α-aminoketones which are expedient precursors for β-aminoalcohol

Full text of DOI:10.1016/S0040-4039(98)01093-4

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