Synthesis of substituted 3-aminocoumarins from ethyl N-2- hydroxyarylideneglycinates

Article abstract of DOI:10.1080/00397919908086261

3-Aminocoumarin and its derivatives are prepared by a thermal (150- 170°C) conversion reaction on the corresponding ethyl N-2- hydroxyarylideneglycinates,[2-HOC₆H₃(X)CH=NCH₂CO₂C₂Hs; X = H, 5-Br, 5- OH, 5-NO₂, 3-OMe, 4-OMe, and 5,6-benzo], which are synthesized by condensing ethyl glycinate hydrochloride with substituted salicylaldehyde.

Full text of DOI:10.1080/00397919908086261

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Synthetic Communications: An
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Synthesis of Substituted 3-
Aminocoumarins from Ethyl N-2-
Hydroxyarylideneglycinates
Lian Ee Khoo a
a National Institute of Education, School of Science Nanyang
Technological University, 469 Bukit Timah Road , Singapore,
259756, SINGAPORE
Published online: 17 Sep 2007.
To cite this article: Lian Ee Khoo (1999) Synthesis of Substituted 3-Aminocoumarins
from Ethyl N-2-Hydroxyarylideneglycinates, Synthetic Communications: An International
Journal for Rapid Communication of Synthetic Organic Chemistry, 29:14, 2533-2537, DOI:
10.1080/00397919908086261
To link to this article: http://dx.doi.org/10.1080/00397919908086261
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