Reactions of 1,3-isothiocyanato ketones with mineral acids. Synthesis of 3,4-dihydro-2H,1,3-thiazin-2-ones

Article abstract of DOI:10.1007/BF01164876

Reactions of 1,3-isothiocyanato ketones with mineral acids formed 3,4-dihydro-2H, 1,3-thiazin-2-ones or their mixtures with 6-alkylidenetetrahydro-1,3-thiazin-2-ones. Subsequent acid hydrolysis of the thiazines obtained formed salts of 1,3-amino ketones. The direction and extent of the transformation depend on the nature of the acid, reaction temperature, and structure of the 1,3-isothiocyanato ketones. 1997 Plenum Publishing Corporation.