Is There Another Common Intermediate beyond Chorismic Acid in the Shikimate Pathway? Synthesis of trans-3--6-hydroxycyclohexa-1,4-diene-1-carboxylic Acid

Article abstract of DOI:10.1021/jo00083a010

As part of a search for mechanistic commonalities uniting the three chorismate-processing enzymes of anthranilate, PABA, and isochorismate biosynthesis,, the title compound 9a, a highly labile allylic isomer of chorismic acid, was prepared by total synthe