Synthesis and antibacterial activity of 2-substituted 5-(1,2-diarylethyl)-4,6-dichloropyrimidine derivatives

Article abstract of DOI:10.1016/0223-5234(96)88279-1

A series of 5-(1,2-diarylethyl)-2,4,6-trichlorapyrimidines and 2-amino- and 2-(1-piperazinyl)-5-(1,2-diarylethyl)-4,6- dichloropyrimidines were synthesized via organozinc reagents. These new pyrimidine derivatives were tested against human bacterial flora