Cobaloxime-Mediated Radical Alkyl-Heteroaromatic Substitution

Article abstract of DOI:10.1021/jo00254a058

The first examples of cobaloxime-mediated radical alkyl-heteroaromatic cross-coupling, replacing a C-H in the protonated heteroaromatic with a C-alkyl, are accomplished via anaerobic visible light photolysis of 95percent EtOH solutions of primary and secondary alkyl cobaloximes, RCo^III(dmgH)2py (dmgH = dimethylglyoxime monoanion), and pyridinium, quinolinium, 4-methylpyridinium, benzothiazolium, and benzimidazolium p-toluenesulfonate.