An exploration of the scope for radical-mediated transannular Diels-Alder reactions in polycycle synthesis

Article abstract of DOI:10.1016/S0040-4039(97)10437-3

Treatment of the iododienynone 4 with Bu₃SnH-AIBN results in the formation of the tricyclic enone 6 by way of radical-mediated macrocyclisation, to 5, followed by transannular Diels-Alder reaction. By contrast, similar treatment of 8 produced t