ASYMMETRIC SYNTHESIS OF (S)-METHYL-3-HYDROXYALKANOATES FROM KETENE AND 2,2-DICHLOROALDEHYDES VIA 4-(1,1-DICHLOROALKYL)-2-OXETANONES

DOI: 10.1016/S0040-4039(00)98780-X

Source and publish data:

Tetrahedron Letters p. 4665 - 4668 (1985)

Update date:2022-08-17

Topics:

Authors:

Ketelaar, Peter E.F.

Staring, Emiel G.J.

Wynberg, Hans

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Article abstract of DOI:10.1016/S0040-4039(00)98780-X

Using the quinidine catalyzed cycloaddition reaction of ketene and 2,2-dichloroaldehydes, the preparation of several optically pure (S)-methyl-3-hydroxyalkanoates is reported.

Full text of DOI:10.1016/S0040-4039(00)98780-X

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