Enzymatic and microbial method of preparation of optically active (±) 3-methyl-4-phenyl-4,5-dihydroisoxazole-4-carboxylic acid

Article abstract of DOI:10.1080/00397919708005466

A racemic mixture of ethyl-3-methyl-4-phenyl-4,5-dihydroisoxasole-4-carboxylate was obtained in the 1,3-dipolar intermolecular cycloaddition of ethyl atroponate and aliphatic nitric oxide, which was then subjected to enzymatic and microbiological hydrolysis in order to obtain optically active acids.

Full text of DOI:10.1080/00397919708005466

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Synthetic Communications: An
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Organic Chemistry
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Enzymatic and Microbial
Method of Preparation of
Optically Active (±) 3-Methyl-4-
phenyl-4,5-dihydroisoxazole-4-
carboxylic Acid
I. Zadrozna a , J. Kurkowska a & I. Makuch a
a Warsaw University of Technology, Faculty of
Chemistry
Published online: 22 Aug 2006.
To cite this article: I. Zadrozna , J. Kurkowska & I. Makuch (1997) Enzymatic and
Microbial Method of Preparation of Optically Active (±) 3-Methyl-4-phenyl-4,5-
dihydroisoxazole-4-carboxylic Acid, Synthetic Communications: An International
Journal for Rapid Communication of Synthetic Organic Chemistry, 27:23, 4181-4191,
DOI: 10.1080/00397919708005466
To link to this article: http://dx.doi.org/10.1080/00397919708005466
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