(8β)-Ergoline-8-carboxylic acid cycloalkyl esters as serotonin antagonists: Structure-activity study

DOI: 10.1021/jm00397a030

Source and publish data:

Journal of Medicinal Chemistry p. 444 - 448 (1988)

Update date:2022-08-17

Topics:

Authors:

Garbrecht

Marzoni Marzoni

Whitten Whitten

Cohen Cohen

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00397a030

A series of (8β)-6-methyl-1-(1-methylethyl)ergoline-8-carboxylic acid cycloalkyl esters were prepared and examined for blockade of vascular 5HT₂ receptors. The antagonist in this series that had the highest 5HT₂ receptor affinity was

Full text of DOI:10.1021/jm00397a030

Products guided by the article

Product name:4-Oxocyclohexan-1-ol p-toluenesulfonate

Cas No:23511-04-8

R&D Labs maybe for 23511-04-8

Shanxi Tongji Pharmaceuticals Co., Ltd.

Contact:+86-359-3024784

Address:Xikuang South Road, Ruicheng County , Shanxi
Zhejiang PRIMAR Import & Export Trade Co., Ltd.

Contact:86-570-3630818

Address:No.1Puzhuyuan,Quhua,Zhejiang Province,China324004
Zouping Fuhai Technology Development Co., Ltd.

Contact:+0532-86934525 18660293207

Address:jiuhu town industrial park Zouping County,bingzhou Provincejiuhu town industrial park
Huayi Isotopes Co.

Contact:+ 86 512 52491118

Address:1 Fuyu Road, Haiyu TownChangshu, Jiangsu, China
Wuhan New-Rise Biochem Co,. Ltd

Contact:+86-13667132959

Address:Wuhan

Relevant to this article

Conjugate addition to diethyl azodicarboxylate under organic- perfluorinated biphasic homogeneous catalysis by nickel(II) species

Doi:10.1016/S0040-4039(00)00549-9
(2000)
VIBRATIONAL SPECTRA OF THE HYDRAZIDES OF (TETRAZOL-1-YL)- AND (TETRAZOL-2-YL)ACETIC ACIDS AND THEIR DEUTERATED ANALOGS

Doi:10.1007/BF00633219
(1991)
Cerium(IV) sulfate tetrahydrate: A catalytic and highly chemoselective deprotection of THP, MOM, and BOM ethers

Doi:10.1016/j.tetlet.2013.10.117
(2013)
Enantiomerically pure α-pinene derivatives from material of 65% enantiomeric purity. Part 2: C₂-symmetric N,N′-3-(2α- hydroxy)pinane diimines and diamines

Doi:10.1016/j.tetasy.2006.01.033
(2006)
Engineering Biofilms for Biocatalysis

Doi:10.1002/cbic.201100200
(2011)
Syntheses, crystal structures, and antimicrobial activities of nickel(II) and cadmium(II) complexes with 4-methylsulfonyl cinnamate and diamines

Doi:10.1080/00958972.2012.744001
(2012)

Article Doi