
Angewandte Chemie - International Edition in English p. 1520 - 1522 (1997)
Update date:2022-08-17
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The elusive aldehyde 1 has never been trapped nor detected during the enzymatic oxidation of UDP-glucose to UDP-glucuronic acid. Here the synthesis of 1 is reported; it proved to be kinetically competent to serve as an intermediate in the reaction catalyzed by UDP-glucose dehydrogenase.
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