Reactions of α-chloro β-oxo aldehydes with CH-acid anions

Article abstract of DOI:10.1007/BF02496260

The reactions of α-chloro and α,α-dichloro β-oxo aldehydes with carbanions are accompanied by the cleavage of the carbon-carbon bond in the chloro aldehydes and result in formylation of CH-acids. These electrophiles react with carbanions, which are generated in situ from CH-acids in the presence of AcONa in aprotic solvents, to form polyfunctional hydroxy compounds.