Synthesis and conformation of unsubstituted calix[4]arene

Article abstract of DOI:10.1016/S0040-4039(00)93521-4

The title compound was prepared and its structure was investigated by single-crystal X-ray diffractometry. The conformation of the molecule in the crystalline state was found to be different from those conformations formerly reported for substituted calix[4]arenes. Molecular mechanics calculations indicate that the conformation in the crystal does not represent an energy minimum.