An improved and simple synthesis of methyl or ethyl 7-oxoheptanoate and 7-acetoxyheptanal

Article abstract of DOI:10.1080/00397919108019797

Reaction of cycloheptanone with potassium persulfate, in ethanol or methanol, gave ethyl or methyl 7-hydroxyheptanoate which, by oxidation with PCC, were converted into ethyl or methyl 7-oxoheptanoate in good yields. Protection of aldehyde group of methyl 7-oxoheptanoate, followed by one-step conversion of carboxylic ester to the acetate gave, after regeneration of aldehyde group, 7-acetoxyheptanal.

Full text of DOI:10.1080/00397919108019797

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Synthetic Communications: An
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An Improved and Simple
Synthesis of Methyl or Ethyl
7-Oxoheptanoate and 7-
Acetoxyheptanal
Roberto Ballini a , Enrico Marcantoni a & Marino
Petrini a
a Dipartimento di Scienze , Chimiche dell'Università
, Via S. Agostino, 1, 62032, Camerino, Italy
Published online: 23 Sep 2006.
To cite this article: Roberto Ballini , Enrico Marcantoni & Marino Petrini (1991)
An Improved and Simple Synthesis of Methyl or Ethyl 7-Oxoheptanoate and
7-Acetoxyheptanal, Synthetic Communications: An International Journal for
Rapid Communication of Synthetic Organic Chemistry, 21:8-9, 1075-1081, DOI:
10.1080/00397919108019797
To link to this article: http://dx.doi.org/10.1080/00397919108019797
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