Evidence for an intramolecular elimination mechanism in the aqueous decomposition of (N-Cl)-alcoholamines

Article abstract of DOI:10.1016/S0040-4020(96)01145-3

(N-Cl)-alcoholamines decompose in aqueous medium through two main reaction paths: an intramolecular elimination and a fragmentation. Both mechanisms take place following a pre-equilibrium deprotonation of the β-hydroxyl group of the (N-Cl)-compound. Evidences for both pathways are given and a very high effective molarity (EM = 0.2 · 10⁶ M) is reported for, the intramolecular process.