Journal of Pharmaceutical Sciences p. 348 - 350 (1989)
Update date:2022-08-11
Topics:
Bergh
Breytenbach
Wessels
Trimethoprim undergoes thermally and photochemically catalyzed hydrolysis or oxidation to give rise to at least five products. The structures of these compounds were determined by physical methods and it was found that the resonance of C-5 in the 13C NMR spectrum is indicative of the substitution pattern of the resultant amino hydroxy pyrimidines.
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