Journal of Organic Chemistry p. 284 - 290 (1994)
Update date:2022-08-11
Topics:
Marson, Charles M.
Grabowska, Urszula
Walsgrove, Timothy
Eggleston, Drake S.
Baures, Paul W.
A new condensation of 3-alkenamides with benzaldehyde in acidic media, notably polyphosphoric acid, lead to γ-lactam rings with high regio- and stereocontrol.One such γ-lactam was shown to undergo a novel and stereocontrolled ring-expansion to a δ-lactam.
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