An efficient synthesis of 6-oxo-17-β-estradiol and its O-carboxymethyl oxime

Article abstract of DOI:10.1080/00397919808005713

Estradiol was efficiently oxidized into 6-oxo estradiol using pyridinium chlorochromate. Previously reported yields were considerably increased by the use of oxidizing agent adsorbed onto celite. The oxo compound was then transformed into the corresponding O-carboxymethy] oxime derivative in quantitative yield.

Full text of DOI:10.1080/00397919808005713

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An Efficient Synthesis of 6-
Oxo-17-β-Estradiol and its O-
Carboxymethyl Oxime
a
a
Stéphane Mons , Luc Lebeau & Charles
a
Mioskowski
a
Université Louis Pasteur, Laboratoire de
Synthèse Bioorganique associé au CNRS - Faculté
de Pharmacie , 74, route du Rhin, BP , 24 -
67401 , Illkirch , France
Published online: 21 Aug 2006.
To cite this article: Stéphane Mons , Luc Lebeau & Charles Mioskowski (1998)
An Efficient Synthesis of 6-Oxo-17-β-Estradiol and its O-Carboxymethyl Oxime,
Synthetic Communications: An International Journal for Rapid Communication of
Synthetic Organic Chemistry, 28:2, 213-218, DOI: 10.1080/00397919808005713
To link to this article: http://dx.doi.org/10.1080/00397919808005713
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