Glucose isomerase catalysed isomerisation reactions of (2 R,3 R)- configured aldofuranoses into the corresponding open-chain 2-ketoses

Article abstract of DOI:10.1016/S0008-6215(97)00206-1

Immobilised glucose isomerase (EC 5.3.1.5) accepted various (2 R,3R)- configured aldofuranoses such as D-erythrose, as well as homologous C-5- modified o-ribose derivatives, as substrates. In the case of D-erythrose, quantitative conversion into D-glycero-tetrulose took place. D-Ribofuranoses were converted into the corresponding open-chain 2-ketoses in isolated yields of 65%. Surprisingly, L-erythrose also turned out to be a substrate of this enzyme.