Tetrahedron p. 7609 - 7614 (1991)
Update date:2022-08-30
Topics:
Adam, Solange
A new practical and high yielding synthesis of mefloquine (1) is described. Heteroarylation of 2-pyridylacetonitrile (2) gave the key intermediate 2-pyridyl-4-quinolylacetonitrile 4, which, on reaction with m-chloroperbenzoic acid, gave unexpectedly the cyanhydrine 5 The later, after base treatment afforded quantitatively the ketone 6.
View More
Quhua Zhongxing Refrigeration Technology Co.,Ltd.
Contact:+86-5708886618
Address:318 Bulding 2, No.866 Quhua Rd.,Kecheng District
Jiangxi Dongbang Pharmaceutical Co., Ltd.
Contact:+86-795-4433603, 4433388
Address:Fengxin Industrial Park, Fengxin County, Jiangxi Province, P.R.C
Contact:86-371-63655023
Address:No.85,jinshui road,zhengzhou,China
Contact:+86-25-83719363
Address:106-7 Chunnan Rd, Chunxi Town, Gaochun, Nanjing, China
Hangzhou yi lu biont technology Co., LTD
Contact:+86-571-88152630
Address:Hangzhoushi HuafengRoad Yicheng3Building1001room.
Doi:10.1016/j.susc.2007.07.018
(2007)Doi:10.1021/jo9004475
(2009)Doi:10.1016/S0022-328X(00)82642-X
(1971)Doi:10.1016/j.catcom.2014.02.019
(2014)Doi:10.1246/bcsj.56.2855
(1983)Doi:10.1016/j.tetlet.2009.02.010
(2009)
